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If this device evolves itself into a clinically applicable
device, it will be of benefit to the mankind.
Dr. A.P.J. Abdul Kalam
Hon. President of India
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Ramamoorthy Ramaswamy,1 Krishnamoorthy Ramaswamy,1 Ramaswamy Ganapathy,1
1Dept of
Medicine, Sri Ramakrishna Hospital, Dharmapuri, Tamilnadu, India.
Background :
Millions of people through out the world face fatal haemodynamic
complications related to acute heart failure. Despite pharmacological advances
the mortality is raising.
Objective : To design a circulatory assist pump that is simpler than the IABP
that also combines direct LV unloading with counterpulsation coronary filling, a
concept which has been shown to provide excellent support for the failing heart.
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Research design : The collapsible membrane pump (CMP) is a LV assist device
placed intracorporeally with a dual valve mechanism. The catheter will be
introduced via a superficial artery with its distal tip positioned in the LV.
During diastole blood is aspirated into the collapsible chamber positioned in
the descending aorta. The collapsible chamber gets distended which now acts to
augment the diastolic coronary filling. During systole the chamber is compressed
and blood is ejected into the ascending aorta. Collapsible chamber will be a
reinforced polyurethane sac and works by an actuator mechanism placed in vitro.
The dual membrane valves works by a simple flap valve mechanism.
Results : Preliminary computer aided simulation studies (Computational Fluid and
Dynamics and Non Linear stress analysis of the material) shows promising
results. This device will directly unload the left ventricle decreasing the work
load, oxygen demand, and increases coronary perfusion.
Conclusion : Our initial results are promising. We feel that the CMP
could soon provide a cheaper, more efficient alternative to the other
conventional short term ventricular assist devices in the management of acute
LVF.
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